RSPO2 antibody (AA 190-218)

Catalog No. ABIN7871604

The Rabbit Polyclonal anti-RSPO2 antibody is suitable to detect RSPO2 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for RSPO2 antibody (AA 190-218) (ABIN7871604)

Target: RSPO2 (R-Spondin 2 (RSPO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPO2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RSPO2 Antibody

Binding Specificity: AA 190-218

Purpose: RSPO2 Antibody / R-spondin-2

Purification: Antigen affinity

Immunogen: A portion of amino acids 190-218 from the human protein was used as the immunogen for this RSPO2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the RSPO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the RSPO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RSPO2

Target: RSPO2 (R-Spondin 2 (RSPO2))

Alternative Name: RSPO2

Background: RSPO2 is a member of the R-spondin family of proteins, which are known for their ability to regulate the Wnt signaling pathway. This pathway plays a crucial role in cell proliferation, differentiation, and stem cell maintenance. RSPO2 specifically has been shown to enhance Wnt signaling, leading to increased cell growth and tissue regeneration. Research on RSPO2 is still in its early stages, but some studies have already shown promising results. For example, a study published in the journal Cell Stem Cell found that RSPO2 can enhance the regenerative capacity of intestinal stem cells, potentially leading to new treatments for diseases like inflammatory bowel disease.

UniProt: Q6UXX9