ARID1A antibody (AA 1900-2000)

Catalog No. ABIN7871649

The Mouse Monoclonal anti-ARID1A antibody is suitable to detect ARID1A in samples from Human. It has been validated for IHC (p).

Quick Overview for ARID1A antibody (AA 1900-2000) (ABIN7871649)

Target: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARID1A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ARID1A-7735

Product Details anti-ARID1A Antibody

Binding Specificity: AA 1900-2000

Purpose: ARID1A Antibody

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1900-2000) from the human protein was used as the immunogen for the ARID1A antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the ARID1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ARID1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ARID1A

Target: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Alternative Name: ARID1A

Background: The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.

UniProt: O14497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation