MYBL1 antibody (AA 199-752)

Catalog No. ABIN7871757

The Rabbit Polyclonal anti-MYBL1 antibody is suitable to detect MYBL1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for MYBL1 antibody (AA 199-752) (ABIN7871757)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-MYBL1 Antibody

Binding Specificity: AA 199-752

Purpose: Myb-related protein A Antibody / A-Myb / MYBL1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K199-L752) was used as the immunogen for the Myb-related protein A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Myb-related protein A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Myb-related protein A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Alternative Name: Myb-related protein A

Background: Myb-related protein A is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

UniProt: P10243

Pathways: Cell Division Cycle, Chromatin Binding