Histone H2A antibody (AA 2-121)

Catalog No. ABIN7871774

This Rabbit Polyclonal antibody specifically detects Histone H2A in WB, ELISA, IHC (p), FACS and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Histone H2A antibody (AA 2-121) (ABIN7871774)

Target: Histone H2A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-Histone H2A Antibody

Binding Specificity: AA 2-121

Purpose: Histone H2AX Antibody

Purification: Affinity purified

Immunogen: Amino acids S2-T121 from the human protein were used as the immunogen for the Histone H2AX antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Histone H2AX antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the Histone H2AX antibody at -20oC.

Target Details for Histone H2A

Target: Histone H2A

Background: H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from theH2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

UniProt: P16104