PNN antibody (AA 2-241)

Catalog No. ABIN7871787

The Rabbit Polyclonal anti-PNN antibody is suitable to detect PNN in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for PNN antibody (AA 2-241) (ABIN7871787)

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PNN Antibody

Binding Specificity: AA 2-241

Purpose: Pinin Antibody / PNN / DRSP

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids A2-L241) was used as the immunogen for the Pinin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Pinin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Pinin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PNN

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Alternative Name: Pinin

Background: Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75/SRSF4, SRM300/SRRM2, and SRRP130/PNISR. Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.

UniProt: Q9H307