EGR1 antibody (AA 2-38)

Catalog No. ABIN7871806

The Rabbit Polyclonal anti-EGR1 antibody (ABIN7871806) specifically detects EGR1 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EGR1 antibody (AA 2-38) (ABIN7871806)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-EGR1 Antibody

Binding Specificity: AA 2-38

Purpose: Early growth response protein 1 Antibody / EGR1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A2-M38) was used as the immunogen for the Early growth response protein 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Early growth response protein 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Early growth response protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Alternative Name: Early growth response protein 1

Background: Early growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a cancer suppressor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity