PPAN antibody (AA 20-288)

Catalog No. ABIN7871856

The Rabbit Polyclonal anti-PPAN antibody is suitable to detect PPAN in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for PPAN antibody (AA 20-288) (ABIN7871856)

Target: PPAN (Peter Pan Homolog (PPAN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PPAN Antibody

Binding Specificity: AA 20-288

Purpose: PPAN Antibody / Suppressor of SWI4 1 homolog

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R20-E288) was used as the immunogen for the PPAN antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PPAN antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PPAN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PPAN

Target: PPAN (Peter Pan Homolog (PPAN))

Alternative Name: PPAN

Background: Suppressor of SWI4 1 homolog is a protein that in humans is encoded by the PPAN gene. The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

UniProt: Q9NQ55