Recombinant OLIG2 antibody (AA 200-300)

Catalog No. ABIN7871941

The Rabbit Monoclonal anti-OLIG2 antibody (Clone OLIG2-6695R) (ABIN7871941) specifically detects OLIG2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant OLIG2 antibody (AA 200-300) (ABIN7871941)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OLIG2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OLIG2-6695R

Product Details anti-OLIG2 Antibody

Binding Specificity: AA 200-300

Purpose: Recombinant OLIG2 Antibody

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 200-300 was used as the immunogen for the recombinant OLIG2 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant OLIG2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant OLIG2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Alternative Name: OLIG2

Background: Olig2, a basic helix loop helix transcription factor, is involved in oligo-dendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue.

UniProt: Q13516