SGSH antibody (AA 206-502)

Catalog No. ABIN7872102

The Rabbit Polyclonal anti-SGSH antibody is suitable to detect SGSH in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for SGSH antibody (AA 206-502) (ABIN7872102)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SGSH Antibody

Binding Specificity: AA 206-502

Purpose: SGSH Antibody / N-sulphoglucosamine sulphohydrolase / HSS

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R206-L502) was used as the immunogen for the SGSH antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SGSH antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SGSH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: SGSH

Background: N-sulphoglucosamine sulphohydrolase is an enzyme that in humans is encoded by the SGSH gene. This gene encodes the enzyme sulfamidase, one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process