The stated application concentrations are suggested starting points. Titration of the PRRT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PRRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
PRRT2
(Proline-Rich Transmembrane Protein 2 (PRRT2))
Alternative Name
PRRT2
Background
As a component of the outer core of AMPAR complex, Proline-rich transmembrane protein 2 may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca2+-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. [UniProt]