NOX5 antibody (AA 21-765)

Catalog No. ABIN7872181

The Rabbit Polyclonal anti-NOX5 antibody (ABIN7872181) specifically detects NOX5 in WB, ELISA, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NOX5 antibody (AA 21-765) (ABIN7872181)

Target: NOX5 (NADPH Oxidase 5 (NOX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NOX5 Antibody

Binding Specificity: AA 21-765

Purpose: NOX5 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids A21-F765) was used as the immunogen for the NOX5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NOX5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NOX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NOX5

Target: NOX5 (NADPH Oxidase 5 (NOX5))

Alternative Name: NOX5

Background: NOX5 (Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. It is found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, NOX5 was identified as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.

UniProt: Q96PH1

Pathways: Proton Transport