DIABLO antibody (AA 211-239)

Catalog No. ABIN7872187

The Rabbit Polyclonal anti-DIABLO antibody (ABIN7872187) specifically detects DIABLO in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for DIABLO antibody (AA 211-239) (ABIN7872187)

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIABLO antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DIABLO Antibody

Binding Specificity: AA 211-239

Purpose: SMAC/Diablo Antibody

Purification: Purified

Immunogen: A portion of amino acids 211-239 from the human protein was used as the immunogen for the SMAC/Diablo antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SMAC/Diablo antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SMAC/Diablo antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DIABLO

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Alternative Name: SMAC/Diablo

Background: SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.

UniProt: Q9NR28

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity