PAX5 antibody (AA 217-282)

Catalog No. ABIN7872247

The Mouse Monoclonal anti-PAX5 antibody (Clone 6I4) (ABIN7872247) specifically detects PAX5 in WB, IHC (p) and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PAX5 antibody (AA 217-282) (ABIN7872247)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 6I4

Product Details anti-PAX5 Antibody

Binding Specificity: AA 217-282

Purpose: PAX5 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids R217-A282) was used as the immunogen for the PAX5 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the PAX5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PAX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background: Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

UniProt: Q02548