ADAM10 antibody (AA 217-311)

Catalog No. ABIN7872248

This Rabbit Polyclonal antibody specifically detects ADAM10 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for ADAM10 antibody (AA 217-311) (ABIN7872248)

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ADAM10 Antibody

Binding Specificity: AA 217-311

Purpose: ADAM10 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A217-D311) was used as the immunogen for the ADAM10 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ADAM10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ADAM10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: ADAM10

Background: A Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by the ADAM10 gene. Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway