EZH2 antibody (AA 22-345)

Catalog No. ABIN7872320

This Rabbit Polyclonal antibody specifically detects EZH2 in WB, ELISA, FACS and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EZH2 antibody (AA 22-345) (ABIN7872320)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EZH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-EZH2 Antibody

Binding Specificity: AA 22-345

Purpose: EZH2 Antibody

Purification: Affinity purified

Immunogen: Amino acids E22-T345 from the human protein were used as the immunogen for the EZH2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EZH2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the EZH2 antibody at -20oC.

Target Details for EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Alternative Name: EZH2

Background: Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme encoded by EZH2gene. It is mapped to 7q36.1. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation