ADAM22 antibody (AA 223-829)

Catalog No. ABIN7872380

This Rabbit Polyclonal antibody specifically detects ADAM22 in WB, ELISA, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAM22 antibody (AA 223-829) (ABIN7872380)

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAM22 Antibody

Binding Specificity: AA 223-829

Purpose: ADAM22 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S223-R829) was used as the immunogen for the ADAM22 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ADAM22 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ADAM22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ADAM22

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Alternative Name: ADAM22

Background: Disintegrin and metalloproteinase domain-containing protein 22 also known as ADAM22 is an enzyme that in humans is encoded by the ADAM22 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

UniProt: Q9P0K1