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Recombinant Synaptophysin antibody (AA 224-313)

This Rabbit Monoclonal antibody specifically detects Synaptophysin in IHC (p). It exhibits reactivity toward Human.
Catalog No. ABIN7872386
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for Recombinant Synaptophysin antibody (AA 224-313) (ABIN7872386)

Target

See all Synaptophysin (SYP) Antibodies
Synaptophysin (SYP)

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

  • 119
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Monoclonal

Conjugate

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This Synaptophysin antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade

Carrier-free

Clone

SYP-4503R
  • Binding Specificity

    • 28
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    AA 224-313

    Purpose

    Recombinant Synaptophysin Antibody (azide and preservative free)

    Purification

    Protein A affinity chromatography

    Immunogen

    A portion of amino acids 224-313 from the human protein was used as the immunogen for the recombinant Synaptophysin antibody.

    Isotype

    IgG
  • Application Notes

    Optimal dilution of the recombinant Synaptophysin antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the recombinant Synaptophysin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Target

    Synaptophysin (SYP)

    Alternative Name

    Synaptophysin

    Background

    This recombinant rabbit monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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