LGI4 antibody (AA 225-531)

Catalog No. ABIN7872402

The Rabbit Polyclonal anti-LGI4 antibody is suitable to detect LGI4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p), IF and FACS.

Quick Overview for LGI4 antibody (AA 225-531) (ABIN7872402)

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-LGI4 Antibody

Binding Specificity: AA 225-531

Purpose: LGI4 Antibody / Leucine-rich repeat LGI family member 4

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids E225-H531) was used as the immunogen for the LGI4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LGI4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LGI4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LGI4

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Alternative Name: LGI4

Background: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

UniProt: Q8N135