Retinoid X Receptor alpha antibody (AA 226-462)

Catalog No. ABIN7872411

The Mouse Monoclonal anti-Retinoid X Receptor alpha antibody is suitable to detect Retinoid X Receptor alpha in samples from Human, Mouse and Rat. It has been validated for WB and FACS.

Quick Overview for Retinoid X Receptor alpha antibody (AA 226-462) (ABIN7872411)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 5E7-

Product Details anti-Retinoid X Receptor alpha Antibody

Binding Specificity: AA 226-462

Purpose: Retinoid X Receptor alpha Antibody / RXRA

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids A226-T462) was used as the immunogen for the Retinoid X Receptor alpha antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Retinoid X Receptor alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Retinoid X Receptor alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Alternative Name: Retinoid X Receptor alpha

Background: Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded by the RXRA gene. Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C