GATA2 antibody (AA 23-288)

Catalog No. ABIN7872522

The Rabbit Polyclonal anti-GATA2 antibody is suitable to detect GATA2 in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for GATA2 antibody (AA 23-288) (ABIN7872522)

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-GATA2 Antibody

Binding Specificity: AA 23-288

Purpose: GATA2 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids D23-S288) was used as the immunogen for the GATA2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GATA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GATA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GATA2

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Alternative Name: GATA2

Background: GATA2 (GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

UniProt: P23769

Pathways: Stem Cell Maintenance