Recombinant PAX5 antibody (AA 235-382)

Catalog No. ABIN7872611

This Mouse Monoclonal antibody specifically detects PAX5 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant PAX5 antibody (AA 235-382) (ABIN7872611)

Target: PAX5 (Paired Box 5 (PAX5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RPAX5-4228

Product Details anti-PAX5 Antibody

Binding Specificity: AA 235-382

Purpose: Recombinant PAX5 Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 235-382 from the human protein was used as the immunogen for the recombinant PAX5 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the recombinant PAX5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant PAX5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background: The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

UniProt: Q02548