SPTAN1 antibody (AA 2351-2475)

Catalog No. ABIN7872624

The Mouse Monoclonal anti-SPTAN1 antibody is suitable to detect SPTAN1 in samples from Human. It has been validated for IHC (p).

Quick Overview for SPTAN1 antibody (AA 2351-2475) (ABIN7872624)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPTAN1-3352

Product Details anti-SPTAN1 Antibody

Binding Specificity: AA 2351-2475

Purpose: Alpha II Spectrin Antibody / Alpha Fodrin / SPTAN1 / NEAS

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 2351-2475) was used as the immunogen for this SPTAN1 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Alpha II Spectrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Alpha II Spectrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Alternative Name: Alpha II Spectrin

Background: Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous II, a neuronal cytoskeleton protein.

UniProt: Q13813

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization