SPTAN1 antibody (AA 2351-2475)

Catalog No. ABIN7872628

The Mouse Monoclonal anti-SPTAN1 antibody (Clone SPTAN1-3374) (ABIN7872628) specifically detects SPTAN1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for SPTAN1 antibody (AA 2351-2475) (ABIN7872628)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: ELISA

Clone: SPTAN1-3374

Product Details anti-SPTAN1 Antibody

Binding Specificity: AA 2351-2475

Purpose: Alpha II Spectrin Antibody / Fodrin / SPTAN1

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human protein (within amino acids 2351-2475) was used as the immunogen for the Alpha II Spectrin antibody.

Isotype: IgG2b, lambda

Application Details

Application Notes: Optimal dilution of the Alpha II Spectrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Alpha II Spectrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Alternative Name: Alpha II Spectrin

Background: Alpha II Spectrin/Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. [UniProt]

UniProt: Q13813

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization