beta 2 Adrenergic Receptor antibody (AA 236-264)

Catalog No. ABIN7872631

The Rabbit Polyclonal anti-beta 2 Adrenergic Receptor antibody (ABIN7872631) specifically detects beta 2 Adrenergic Receptor in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for beta 2 Adrenergic Receptor antibody (AA 236-264) (ABIN7872631)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta 2 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-beta 2 Adrenergic Receptor Antibody

Binding Specificity: AA 236-264

Purpose: B2AR Antibody / Beta-2-Adrenergic receptor / ADRB2

Purification: Antigen affinity

Immunogen: A portion of amino acids 236-264 from the human protein was used as the immunogen for the B2AR antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the B2AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the B2AR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Alternative Name: B2AR

Background: The Beta-2-Adrenergic receptor is a protein that is found on the surface of cells, particularly in the lungs, heart, and smooth muscle tissue. It is a member of the G-protein coupled receptor family which transmits signals from outside the cell to the inside, triggering a cascade of cellular responses. The Beta-2-Adrenergic receptor plays a critical role in regulating various physiological functions, including bronchodilation, heart rate, and glucose metabolism. Dysregulation of the Beta-2-Adrenergic receptor has been implicated in a variety of diseases, such as asthma, chronic obstructive pulmonary disease, and heart failure.

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation