ATR antibody (AA 24-1324)

Catalog No. ABIN7872663

The Rabbit Polyclonal anti-ATR antibody is suitable to detect ATR in samples from Human. It has been validated for ELISA and IF.

Quick Overview for ATR antibody (AA 24-1324) (ABIN7872663)

Target: ATR (ATR serine/threonine kinase (ATR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATR antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-ATR Antibody

Binding Specificity: AA 24-1324

Purpose: ATR Antibody / Ataxia telangiectasia and Rad3-related protein / FRP1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E24-D1324) was used as the immunogen for the ATR antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATR

Target: ATR (ATR serine/threonine kinase (ATR))

Alternative Name: ATR

Background: Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus