The Rabbit Polyclonal anti-CYB5R3 antibody (ABIN7872679) specifically detects CYB5R3 in WB, ELISA, IF and FACS.
The antibody is reactive with Human, Rat and Mouse samples.
CYB5R3
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
2A9
unconjugated
Application Notes
Optimal dilution of the CYB5R3 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the CYB5R3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
CYB5R3
(Cytochrome B5 Reductase 3 (CYB5R3))
Alternative Name
CYB5R3
Background
NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.