Apelin antibody (AA 24-77)

Catalog No. ABIN7872721

The Rabbit Polyclonal anti-Apelin antibody (ABIN7872721) specifically detects Apelin in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Apelin antibody (AA 24-77) (ABIN7872721)

Target: Apelin (APLN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Apelin Antibody

Binding Specificity: AA 24-77

Purpose: APLN Antibody / APEL / Apelin

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S24-F77) was used as the immunogen for the APLN antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the APLN antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the APLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Apelin

Target: Apelin (APLN)

Alternative Name: APLN

Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

UniProt: Q9ULZ1

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour