CCL7 antibody (AA 24-97)

Catalog No. ABIN7872724

The Rabbit Polyclonal anti-CCL7 antibody (ABIN7872724) specifically detects CCL7 in WB and ELISA. The antibody is reactive with Rat samples.

Quick Overview for CCL7 antibody (AA 24-97) (ABIN7872724)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL7 Antibody

Binding Specificity: AA 24-97

Purpose: Ccl7 Antibody / Mcp3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant rat protein (amino acids Q24-P97) was used as the immunogen for the Ccl7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ccl7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Ccl7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: Ccl7

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

UniProt: Q9QXY8