PAX2A antibody (AA 240-282)

Catalog No. ABIN7872729

The Rabbit Polyclonal anti-PAX2A antibody is suitable to detect PAX2A in samples from Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PAX2A antibody (AA 240-282) (ABIN7872729)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAX2A Antibody

Binding Specificity: AA 240-282

Purpose: Zebrafish Pax2 Antibody / Pax2a / Pax2b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Pax2 recombinant protein (amino acids E240-Q282) was used as the immunogen for the Zebrafish Pax2 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Pax2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Pax2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Alternative Name: Pax2

Background: Paired box gene 2, also known as PAX2, is a protein which in humans is encoded by the PAX2 gene. This gene is mapped to 10q24. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

UniProt: Q90268

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation