Exonuclease 1 antibody (AA 25-846)

Catalog No. ABIN7872894

The Rabbit Polyclonal anti-Exonuclease 1 antibody is suitable to detect Exonuclease 1 in samples from Human. It has been validated for WB, ELISA, IP and IF.

Quick Overview for Exonuclease 1 antibody (AA 25-846) (ABIN7872894)

Target: Exonuclease 1 (EXO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: AA 25-846

Purpose: EXO1 Antibody / Exonuclease 1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q25-Q846) was used as the immunogen for the EXO1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EXO1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the EXO1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1

Background: Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

UniProt: Q9UQ84

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response