SH3BP2 antibody (AA 256-561)

Catalog No. ABIN7872952

The Rabbit Polyclonal anti-SH3BP2 antibody (ABIN7872952) specifically detects SH3BP2 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for SH3BP2 antibody (AA 256-561) (ABIN7872952)

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SH3BP2 Antibody

Binding Specificity: AA 256-561

Purpose: 3BP2 Antibody / SH3 domain-binding protein 2 / SH3BP2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R256-R561) was used as the immunogen for the 3BP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the 3BP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the 3BP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SH3BP2

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Alternative Name: 3BP2

Background: SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P78314

Pathways: TCR Signaling