IL1RL2 antibody (AA 257-286)

Catalog No. ABIN7872954

The Rabbit Polyclonal anti-IL1RL2 antibody is suitable to detect IL1RL2 in samples from Human. It has been validated for WB and FACS.

Quick Overview for IL1RL2 antibody (AA 257-286) (ABIN7872954)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IL1RL2 Antibody

Binding Specificity: AA 257-286

Purpose: IL1RL2 Antibody / Interleukin-1 receptor-like 2

Purification: Antigen affinity

Immunogen: A portion of amino acids 257-286 from the human protein was used as the immunogen for this IL1RL2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the IL1RL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the IL1RL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Alternative Name: IL1RL2

Background: IL1RL2, also known as interleukin-1 receptor-like 2, is a protein that belongs to the IL-1 receptor family. It is primarily expressed on the surface of immune cells, where it binds to specific ligands and triggers a cascade of signaling pathways that ultimately lead to the activation of immune responses. Studies have shown that IL1RL2 plays a critical role in the pathogenesis of various inflammatory diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. One of the key functions of IL1RL2 is its ability to regulate the production of pro-inflammatory cytokines, such as IL-6 and IL-8, which are responsible for promoting inflammation in the body. By modulating the activity of these cytokines, IL1RL2 helps to maintain the balance between pro-inflammatory and anti-inflammatory responses, thereby preventing excessive inflammation and tissue damage. Furthermore, IL1RL2 has also been shown to play a role in the activation of T cells and other immune cells, which are essential for mounting an effective immune response against pathogens.

UniProt: Q9HB29