Recombinant IL3RA antibody (AA 26-171)

Catalog No. ABIN7872984

The Mouse Monoclonal anti-IL3RA antibody is suitable to detect IL3RA in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant IL3RA antibody (AA 26-171) (ABIN7872984)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RIL3RA-9212

Product Details anti-IL3RA Antibody

Binding Specificity: AA 26-171

Purpose: Recombinant IL3RA Antibody / Interleukin 3 Receptor alpha / CD123

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human IL3RA protein (within amino acids 26-171) was used as the immunogen for the recombinant IL3RA antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the recombinant IL3RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant IL3RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA

Background: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

UniProt: P26951

Pathways: JAK-STAT Signaling