ULBP1 antibody (AA 27-209)

Catalog No. ABIN7873093

The Rabbit Polyclonal anti-ULBP1 antibody (ABIN7873093) specifically detects ULBP1 in ELISA, WB, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ULBP1 antibody (AA 27-209) (ABIN7873093)

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULBP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ULBP1 Antibody

Binding Specificity: AA 27-209

Purpose: ULBP1 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids W27-K209) was used as the immunogen for the ULBP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ULBP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ULBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Alternative Name: ULBP1

Background: UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process