Growth Hormone 1 antibody (AA 27-217)
Quick Overview for Growth Hormone 1 antibody (AA 27-217) (ABIN7873094)
Target
See all Growth Hormone 1 (GH1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 27-217
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Purpose
- GH1 Antibody / Growth Hormone
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Purification
- Antigen affinity purified
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Immunogen
- Recombinant human protein (amino acids F27-F217) was used as the immunogen for the GH1 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the GH1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the GH1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Growth Hormone 1 (GH1)
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Alternative Name
- GH1
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Background
- Growth Hormone (GH) is mapped to 17q22-q24. Growth hormone (GH) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.
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UniProt
- P01241
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Pathways
- NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
Target
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