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Recombinant Synaptophysin antibody (AA 274-313)

The Rabbit Monoclonal anti-Synaptophysin antibody is suitable to detect Synaptophysin in samples from Human. It has been validated for IHC (p).
Catalog No. ABIN7873200
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for Recombinant Synaptophysin antibody (AA 274-313) (ABIN7873200)

Target

See all Synaptophysin (SYP) Antibodies
Synaptophysin (SYP)

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This Synaptophysin antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade

Carrier-free

Clone

SYP-7976R
  • Binding Specificity

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    AA 274-313

    Purpose

    Synaptophysin Antibody / SYP (azide and preservative free)

    Purification

    Protein A/G affinity

    Immunogen

    A recombinant partial protein sequence (within amino acids 274-313) from the human protein was used as the immunogen for the Synaptophysin antibody.

    Isotype

    IgG, kappa
  • Application Notes

    Optimal dilution of the Synaptophysin antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    -20 °C

    Storage Comment

    Aliquot the Synaptophysin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Synaptophysin (SYP)

    Alternative Name

    Synaptophysin

    Background

    This recombinant rabbit monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

    UniProt

    P08247

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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