Recombinant Synaptophysin antibody (AA 274-313)
Quick Overview for Recombinant Synaptophysin antibody (AA 274-313) (ABIN7873200)
Target
See all Synaptophysin (SYP) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Binding Specificity
- AA 274-313
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Purpose
- Synaptophysin Antibody / SYP (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 274-313) from the human protein was used as the immunogen for the Synaptophysin antibody.
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Isotype
- IgG, kappa
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Application Notes
- Optimal dilution of the Synaptophysin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the Synaptophysin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Synaptophysin (SYP)
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Alternative Name
- Synaptophysin
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Background
- This recombinant rabbit monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
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UniProt
- P08247
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
Target
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