Ki-67 antibody (AA 2860-3256)

Catalog No. ABIN7873321

The Mouse Monoclonal anti-Ki-67 antibody (Clone 5E12-) (ABIN7873321) specifically detects Ki-67 in FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Ki-67 antibody (AA 2860-3256) (ABIN7873321)

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ki-67 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5E12-

Product Details anti-Ki-67 Antibody

Binding Specificity: AA 2860-3256

Purpose: Ki-67 Antibody

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K2860-I3256) was used as the immunogen for the Ki-67 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Ki-67 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Ki-67 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Ki-67

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Alternative Name: Ki-67

Background: Ki-67 (Proliferation-related Ki-67 antigen), also known as MKI67 or KIA, is a protein that in humans is encoded by the MKI67 gene. From study of a panel of human-rodent somatic cell hybrids, it has been demonstrated that a gene involved in the expression of the MKI67 antigen is located on chromosome 10. By in situ hybridization, Fonatsch et al. (1991) regionalized the MKI67 gene to chromosome 10q25-qter. By FISH, Traut et al. (1998) mapped the mouse Mki67 gene to chromosome 7F3-F5. Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis.

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process