GPR81 antibody (AA 287-316)

Catalog No. ABIN7873323

The Rabbit Polyclonal anti-GPR81 antibody is suitable to detect GPR81 in samples from Human. It has been validated for WB.

Quick Overview for GPR81 antibody (AA 287-316) (ABIN7873323)

Target: GPR81 (G Protein-Coupled Receptor 81 (GPR81))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR81 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPR81 Antibody

Binding Specificity: AA 287-316

Purpose: HCAR1 Antibody / Hydroxycarboxylic acid receptor 1 / GPR81

Purification: Antigen affinity

Immunogen: A portion of amino acids 287-316 from the human protein was used as the immunogen for the HCAR1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the HCAR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HCAR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GPR81

Target: GPR81 (G Protein-Coupled Receptor 81 (GPR81))

Alternative Name: HCAR1

Background: HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key role in regulating glucose and lipid metabolism. One of the most intriguing aspects of HCAR1 is its ability to promote the use of fats as an energy source, a process known as fatty acid oxidation. By activating HCAR1, the body is able to break down fatty acids more efficiently, leading to improved metabolic health and potentially aiding in weight management. Additionally, HCAR1 has been shown to have anti-inflammatory effects, which can help combat chronic inflammation associated with metabolic disorders such as obesity and diabetes. By modulating the body's immune response, HCAR1 can help reduce inflammation and improve overall health.

UniProt: Q9BXC0