HIF3A antibody (AA 29-480)

Catalog No. ABIN7873426

The Rabbit Polyclonal anti-HIF3A antibody (ABIN7873426) specifically detects HIF3A in WB, ELISA and FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HIF3A antibody (AA 29-480) (ABIN7873426)

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIF3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-HIF3A Antibody

Binding Specificity: AA 29-480

Purpose: HIF3A Antibody / Hypoxia-inducible factor 3 alpha

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Q29-Q480) was used as the immunogen for the HIF3A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HIF3A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HIF3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HIF3A

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Alternative Name: HIF3A

Background: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

UniProt: Q9Y2N7

Pathways: Warburg Effect