LIG3 antibody (AA 297-963)

Catalog No. ABIN7873483

The Rabbit Polyclonal anti-LIG3 antibody (ABIN7873483) specifically detects LIG3 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LIG3 antibody (AA 297-963) (ABIN7873483)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-LIG3 Antibody

Binding Specificity: AA 297-963

Purpose: DNA Ligase 3 Antibody / LIG3

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D297-D963) was used as the immunogen for the DNA Ligase 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DNA Ligase 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DNA Ligase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: DNA Ligase 3

Background: DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P49916

Pathways: DNA Damage Repair