HGS antibody (AA 3-777)

Catalog No. ABIN7873551

The Rabbit Polyclonal anti-HGS antibody is suitable to detect HGS in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, FACS, IP and IHC (p).

Quick Overview for HGS antibody (AA 3-777) (ABIN7873551)

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HGS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HGS Antibody

Binding Specificity: AA 3-777

Purpose: HGS Antibody / HRS / HGF-regulated tyrosine kinase substrate

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids R3-D777) was used as the immunogen for the HGS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HGS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HGS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HGS

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Alternative Name: HGS

Background: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation