Recombinant Desmoglein 3 antibody (AA 300-500)

Catalog No. ABIN7873625

This Rabbit Monoclonal antibody specifically detects Desmoglein 3 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Desmoglein 3 antibody (AA 300-500) (ABIN7873625)

Target: Desmoglein 3 (DSG3)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DSG3-8613R

Product Details anti-Desmoglein 3 Antibody

Binding Specificity: AA 300-500

Purpose: Desmoglein 3 Antibody / DSG3

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 300-500) from the human protein was used as the immunogen for the Desmoglein 3 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Desmoglein 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Desmoglein 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: Desmoglein 3

Background: Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This mAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

UniProt: P32926