EZH2 antibody (AA 300-550)

Catalog No. ABIN7873671

The Mouse Monoclonal anti-EZH2 antibody is suitable to detect EZH2 in samples from Human. It has been validated for IHC (p).

Quick Overview for EZH2 antibody (AA 300-550) (ABIN7873671)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EZH2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EZH2-4687

Product Details anti-EZH2 Antibody

Binding Specificity: AA 300-550

Purpose: Enhancer of zeste homolog 2 Antibody / EZH2 / KTM6

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 300-550) from the human protein was used as the immunogen for the Enhancer of zeste homolog 2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Enhancer of zeste homolog 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Enhancer of zeste homolog 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Alternative Name: Enhancer of zeste homolog 2

Background: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation