SMURF2 antibody (AA 303-387)

Catalog No. ABIN7873725

The Rabbit Polyclonal anti-SMURF2 antibody is suitable to detect SMURF2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SMURF2 antibody (AA 303-387) (ABIN7873725)

Target: SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMURF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMURF2 Antibody

Binding Specificity: AA 303-387

Purpose: SMURF2 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids W303-Q387) was used as the immunogen for the SMURF2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SMURF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SMURF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SMURF2

Target: SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))

Alternative Name: SMURF2

Background: E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs, TGF-beta receptor (TGFBR), and other substrates. It also functions in regulation of neuronal and planar cell polarity, induction of senescence, and tumor suppression.

UniProt: Q9HAU4