TACSTD2 antibody (AA 31-274)

Catalog No. ABIN7873772

This Mouse Monoclonal antibody specifically detects TACSTD2 in IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TACSTD2 antibody (AA 31-274) (ABIN7873772)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TACSTD2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TACSTD2-2152

Product Details anti-TACSTD2 Antibody

Binding Specificity: AA 31-274

Purpose: TROP2 Antibody / TACSTD2

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 31-274 were used as the immunogen for the TROP2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the TROP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the TROP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TACSTD2

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Alternative Name: TROP2

Background: TACSTD2, also called TROP2, is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

UniProt: P09758