IST1 antibody (AA 31-331)
Quick Overview for IST1 antibody (AA 31-331) (ABIN7873781)
Target
See all IST1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 31-331
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Purpose
- IST1 Antibody / CHMP8
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Purification
- Antigen affinity chromatography
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Immunogen
- An E.coli-derived human recombinant protein (amino acids E31-D331) was used as the immunogen for the IST1 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the IST1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the IST1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
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Alternative Name
- IST1
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Background
- IST1 homolog, also called CHMP8 and Charged multivesicular body protein 8, is a protein that in humans is encoded by the IST1 gene. This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- P53990
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Pathways
- Regulation of Cell Size
Target
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