COMP
Reactivity: Human
WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
The stated application concentrations are suggested starting points. Titration of the TSP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the TSP5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
COMP
(Cartilage Oligomeric Matrix Protein (COMP))
Alternative Name
TSP5
Background
COMP/TSP5 is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations.