CA9 antibody (AA 314-410)

Catalog No. ABIN7873858

The Mouse Monoclonal anti-CA9 antibody (Clone CA9-3407) (ABIN7873858) specifically detects CA9 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for CA9 antibody (AA 314-410) (ABIN7873858)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CA9-3407

Product Details anti-CA9 Antibody

Binding Specificity: AA 314-410

Purpose: Carbonic Anhydrase IX Antibody / CA9

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 314-410 from the human protein was used as the immunogen for the Carbonic Anhydrase IX antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Carbonic Anhydrase IX antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Carbonic Anhydrase IX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: Carbonic Anhydrase IX

Background: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

UniProt: Q16790