UBE2K antibody (AA 33-195)

Catalog No. ABIN7873990

The Rabbit Polyclonal anti-UBE2K antibody (ABIN7873990) specifically detects UBE2K in WB, ELISA and FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for UBE2K antibody (AA 33-195) (ABIN7873990)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-UBE2K Antibody

Binding Specificity: AA 33-195

Purpose: Huntingtin interacting protein 2 Antibody / HIP2 / UBE2K

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D33-E195) was used as the immunogen for the Huntingtin interacting protein 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Huntingtin interacting protein 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Huntingtin interacting protein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: Huntingtin interacting protein 2

Background: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

UniProt: P61086