Mu Opioid Receptor 1 antibody (AA 33-321)

Catalog No. ABIN7873997

This Rabbit Polyclonal antibody specifically detects Mu Opioid Receptor 1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Mu Opioid Receptor 1 antibody (AA 33-321) (ABIN7873997)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mu Opioid Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Mu Opioid Receptor 1 Antibody

Binding Specificity: AA 33-321

Purpose: MOR-1 Antibody / Mu-type Opioid Receptor / OPRM1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids N33-H321) was used as the immunogen for the MOR-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MOR-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MOR-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Alternative Name: MOR-1

Background: This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane